Friday, May 8, 2020

Big variances in the mortality...

-First of all, if the rate (mortality) is simply obtained based on the binomial distribution, the variance of the mortality cannot be large especially with large sample sizes (n>1000 or 10000).
 
-What we observe about the variance of mortality of corona seems about 0.02 or so, which is too big considered that the rates are obtained based on hundreds and thousands of people (like state level).

-So, the true death rate is hyper-parameter that we may assume that it has a beta distribution. Thing is that, when the death rate is constant for each state (not every individual has different death rate), the variance is bigger.

-When specificity is high, the variance is a function of sample size (independent of death rate).

-But, when specificity is low, the variance is not decreased with increasing sample size.

- On the other hand, high or low sensitivity does not change much of the variance (independent of death rate). large sample size indeed decreases variance.

-The real death rate based on the generated data is indeed function of death rate and sample size.

- So, the low specificity is the problem. What is the meaning of the low specificity in death?
 A lot of people never get tested - who are mostly healthy. So this whole "system" of detecting "death" has very high specificity because most of them are considered healthy...
???
  

정말로 오랜만에 쓰는구나...

내가 추구하는 것들...
나는 진실을 추구하는듯하다...진리를 추구하는 듯하다.
진리...진리...
반대말은 짜가...짜가가 되고 싶지않다.
반면 나의 능력은 한계가 있고...끊임없이 추구하는 사람이 되어야겠다.
추구...추구...그것이 내가 할수 있는 부분이...지....않...을...까...

해야할일들 꿈꾸는 일들 하고싶은 일들이 산적해 있구나...다시 여름을 시작하는데...이 여름에 여름을 거둘수 있기를 바란다.

1. 준유의 IF를 내가 직접봐야겠다. 시뮬레이션을 완성하도록.
2. 소윤의 brain image - DTI manuscript를 완성할 수 있도록.
3. trauma관련 grant를 apply하고 싶다.
4. 밍메이와 flu manuscript를 완성하자.
5. Zohi의 알츠하이머 연구/데이타를 이해하자.
6. measurement error와 nutrition관련 manuscript를 쓰고 싶다.
7. COVID death rate variances...may be related to underestimates of prevalence.
8. Survival analysis, where Y(t) is random...Population health data...

그럼 오늘은 무엇을 해야하나...
이시간에 zohi data를 일단이해하려해보자.
그리고나서 준유의 프로그램을 자세히 보자.
second derivative를 직접구해보는 것으로...물론 해시안 메트릭스가 정확히 구해지는지도 보고.

내일 한두시간정도는 데이타 콘덴스를 어떻게 할수 있는지 (from micro to macro)페이퍼를 한번 봐보자...

Big variances in the mortality...

-First of all, if the rate (mortality) is simply obtained based on the binomial distribution, the variance of the mortality cannot be large ...